Arterial spin labelling (ASL) is a noninvasive magnetic resonance imaging (MRI) modality, capable of measuring blood perfusion\nwithout the use of a contrast agent. While ASL implementation for imaging the brain and monitoring cerebral blood flow has\nbeen reviewed in depth, the technique is yet to be widely used for ocular tissue imaging. The human retina is a very thin but\nhighly stratified structure and it is also situated close to the surface of the body which is not ideal for MR imaging. Hence, the\napplication of MR imaging and ASL in particular has been very challenging for ocular tissues and retina. That is despite the fact\nthat almost all of retinal pathologies are accompanied by blood perfusion irregularities. In this review article, we have focused on\nthe technical aspects of the ASL and their implications for its optimum adaptation for retinal blood perfusion monitoring. Retinal\nblood perfusion has been assessed through qualitative or invasive quantitativemethods but the prospect of imaging flow using ASL\nwould increase monitoring and assessment of retinal pathologies.The review provides details of ASL application in human ocular\nblood flow assessment.
Loading....